1 in 30 are healthy carriers of cystic fibrosis and can pass it on to their baby. GENES2LIFE can diagnose it before a pregnancy.

GENES2LIFE

Genes2Life is a genetic test used before pregnancy to investigate whether there is a risk of having a child with an inherited genetic disease. Hereditary diseases are inherited through genetic material from one generation to another. In some cases, conditions can skip one generation and be inherited in the next - they are inherited as recessive conditions. Recessive inheritance means that a person can carry disease-related mutations without being aware of them.

Genes Tested: Recessive genes as recommended by ACOG* Range: 93 genes Disease investigated: + 90 diseases

Gene List More information Gene List and Phenotypes

RECESSIVE GENETIC DISEASE

Two copies of the same mutated gene, one in the woman and one in the man, cause the disease.

The Genes2Life panel is regularly updated according to the newest recommendations and knowledge obtained in the field of genetic diseases. The Genes2Life panel is based on the recommendations from ACOG (American College of Obstetricians and Gynecologists).

  • Carrier probability: 1 in 100 couples at risk
  • Characteristics and symptoms related to a known disease
  • Have a detrimental effect on the quality of life
  • Can damage physical and mental ability
  • Require surgical or medical intervention
  • Early-onset disease
  • Can be diagnosed prenatally

Reference: https://pubmed.ncbi.nlm.nih.gov/28697118/

TYPE OF GENETIC DISEASES INVESTIGATED WITH GENE2LIFE:

Genetic diseases: Spinal muscular atrophy. Statistics: 1 in 6000 -10000 children are born with the disease. In the United Kingdom approx. 2000-2500 children and adults live with SMA. Genetic diseases: Cystic Fibrosis. Statistics: Approx. 1 in 30 people is a healthy carrier of cystic fibrosis without knowing it. In Denmark, 1-2 children are born with cystic fibrosis every month. This represents approx. 150000 people in Denmark. Genetic diseases: Lysosomal diseases such as Tay-Sachs, Sandhoffs, Niemann, Gauchers, Mannosidose, Fukosidose, Sialidose, Hurlers, Hunter, Sanfilippos, Morquios, I-cell, Cystinose, Sallas, Wolmans. Statistics: Approx. 70 different lysosomal diseases. Each of these is very rare, but as a group, they affect about 1 in 5000-8000 newborns. Every year, about 10 children are born with one of these diagnoses in Denmark. Reference: https://www.orpha.net/consor/cgi-bin/index.php?lng=EN

WE NEED A BLOOD OR SALIVA SAMPLE FOR THE TEST

WE RECOMMEND THIS TEST:

  • For couples trying to get pregnant.
  • Before starting an assisted fertilization treatment.

HOW TO DO IT?